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Control animals received bilateral icv injection of ACSF on day 1 and day 3

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Activated macrophages have been found to overexpress folate receptor (FR), whose binding on the nanoparticle surface can result in active targeted delivery to the tissues of RA [95]

That can make the obstruction worse. That doesnt mean these drugs are always off-limits if you have both obstructive HCM and high blood pressure

No significant differences in the number or morphology of GFAP-positive astrocytes were observed between any of the treatment groups (Figure 9B)

Clin Infect Dis [Internet]