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Knockout of LAMP-2 hindered autophagosome-lysosome complex formation, resulting in the buildup of autophagosomes, limited zymogen granule degradation, and abnormal trypsinogen activation, exacerbating AP (107, 108)

Lupus is a long-term condition that can cause inflammation in the skin, organs, and in various other places in the body

Jun DW, Kim KT, Lee OY, Chae JD, Son BK, Kim SH, et al

According to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, MUD includes symptoms of craving, an inability to curtail use despite negative consequences, continuing to use methamphetamine at the expense of other activities, the development of tolerance and experiencing a withdrawal syndrome on abrupt cessation of use [3]

For instance, a baby's clothes may often be changed anywhere between two and five times in a single day

Baird L, Yamamoto M (2020) The molecular mechanisms regulating the KEAP1-NRF2 pathway