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Apr 13;15(8) :2286

Using the tripeptide as a new template, additional active analogues were synthesized with improved metabolic stability, blood brain barrier permeability, and oral activity

Pei, J., Pan, X., Wei, G., & Hua, Y

doi: 10.1007/s00204-015-1579-5 39 DAlessandroMCBKanaanSGellerMPraticDDaherJPL

The immobilization enzymes were washed three times with 2 mL of 20 mM potassium phosphate buffer (pH 8.0)

Impaired BBB stability DCE-MRI has exposed increased regional BBB permeability in the cortex and hippocampus in AD, basal ganglia in PD, and white matter in MS