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DK, SF, YL, XY and ZJ provided constructive suggestions for the article and contributed to its design and structuring

One is that the loss of a neuroprotective effect of UA when it is reduced below normal is not necessarily modelled by comparing serum levels in unaffected subjects with the hyperuricemia associated with gout

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The production of thrombin is triggered by the exposure of tissue factors in the arterial wall, which in turn sets off the clotting cascade

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10.1016/j.cmet.2012.12.007 102