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Description

Carcinoma 10, 21732185

Human milk oligosaccharides: Every little one goals a sugar mama

10.1177/0885328217723179 44 FalconeT.FlycktR

PMID: 1371669

Its effects require intact amylin receptor signaling, as demonstrated in receptor knockout models where weight loss is abolished, and structural studies show unique conformational dynamics at these receptors compared to native amylin or other analogs

Other Nrf2-dependent genes, including GPX4, GSH and NADPH synthesis genes, as well as epigenetic regulators of lipid hydroperoxides, contribute to its ferroptosis-inhibitory effects (117119)