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Thus, in this loose-association state, arrestins are unlikely to compete with G proteins to cause uncoupling

Commerford PJ

This observational, prospective, cohort study demonstrates the substantial number of patients with psoriasis who were treated by dermatologists and had undiagnosed PsA, emphasizing the essential role of dermatologists in evaluating patients with psoriasis for joint involvement

doi: 10.1126/sciadv.aaw7123, 115 Ul-HamidA

however, since research studies conducted on the cross talk between EpCAM and the RAS/RAF/MEK/ERK cascade have been limited to recent years and even sometimes are conflicting, it is almost impossible to define a conclusive opinion regarding the cross talk between c-Met and EpCAM through this pathway (Fig