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Commercial development was discontinued in 2007 after the Phase IIb trial failed to meet its primary endpoint

Oligonucleotide purification: Quantitative monitoring via in-line UPLC Asymchem is translating PAT capabilities into tangible process gainsapplying validated methods in active programs to optimize performance and refine critical parameters

Adherence to dosage guidelines is strongly advised

Any solution that gets injected into the body is Rx only

The layout is understated, following a classic out-and-back routing, where especially the outgoing holes provide the most classic experience playing through, among other things, bomb craters of WWII

The prediction accuracy assessment indicates that (research question #2) the best achievable mapping accuracy is RMSE of 17.7 [kg m 3 ] (0.486 in log-scale) for SOC density, RMSE of 51.3 [g kg 1 ] (0.574 in log-scale) for SOC content, RMSE of 0.15 [t m 3 ] for bulk density of fine-earth, RMSE of 0.51 for soil pH, RMSE of 8.4 % for soil clay content, and RMSE of 12.6 % for soil sand content, respectively