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Description

FOXO4-DRI: Senolytic Peptide Mechanism and the p53-FOXO4 Axis FOXO4-DRI is a D-retro-inverso peptide that selectively kills senescent cells by disrupting the protective FOXO4-p53 interaction

The recently reported roles of GSH in defending cells against oxidative stress and its involvement in protein modification and cellular signaling highlight the importance of the maintenance of intracellular GSH for cellular function and viability [48,49]