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For example, as a coenzyme of SOD2, Mn is involved in redox-sensitive reactions that reduce superoxide (O 2 ) to produce H 2 O 2 , which is then further reduced to produce water by either glutathione peroxidase (GPx) or peroxiredoxins (Prxs) 125,126

Daniels, J

Statements that describe disease treatment turn a supplement into a drug

The convergence of mitochondrial redox regulation (via SIRT3SOD2) and hypercholesterolemia-induced hypoxia signaling on NOS1 highlights its centrality in CRC pathophysiology

Sheibani, L

Myoglobin toxicity in proximal human kidney cells: roles of Fe, Ca 2+ , H 2 O 2 , and terminal mitochondrial electron transport