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MS-DRG Context Per the FY2026 ICD-10-CM/PCS MS-DRG v43.1 Definitions Manual (CMS), anemias most commonly group to: DRG 811 : Red Blood Cell Disorders with MCC includes D62, D50.x, D63.x, D64.x as principal diagnoses with MCC DRG 812 : Red Blood Cell Disorders without MCC DRG 808810 : Major Hematological and Immunological Diagnoses (aplastic anemias, acquired hemolytic anemias) with/without MCC/CC D62 (acute posthemorrhagic anemia) is classified as an MCC when it appears as a secondary diagnosis, significantly impacting DRG assignment and reimbursement