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EC 50 a Concentration (nM) of ferrostatin analogue required to achieve 50% viability against HT-1080 cells treated with 10 mM erastin

Melanoma cells arising from the immature melanocytes that have become arrested in the lamina propria of the oral mucosa proliferate, forming nodular aggregates in the lamina propria/submucosa with or without breaching the subepithelial basement membrane

However, these protective effects were abolished in the presence of CC (Fig

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doi: 10.1021/bc060173z