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Poly (2-oxazoline)Based Polyplexes as a PEGFree Plasmid DNA Delivery Platform

By integrating B12 shots into their health regimen, they can ensure they are meeting their nutritional needs without compromising their dietary choices

10.1371/journal.pone.0144234 45 LondonoJ.SaldarriagaE

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However, it is important to note that clinical translation of these approaches does face several challenges: profound metabolic and molecular heterogeneity between patients (and even within tumors), difficulties in achieving adequate drug penetration across the blood-brain barrier, and the risk of toxicity in normal cerebral tissue