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Concomitantly, co-culture with GMSCs under two conditions led to a comparable increase in the secretion of IL-10, a signature anti-inflammatory cytokine of pro-regenerative (M2) macrophages, compared with THP-1 macrophages or GMSCs cultured alone (Fig

Phase I Safety Trial: As noted, a Phase I trial (the first step in testing a drug in humans, usually focused on safety and pharmacokinetics) was registered in 2015, aiming to give BPC-157 to healthy volunteers

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