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In PD patients, misfolded -synuclein is released from injured neurons into the extracellular fluid, where it binds to Toll-like receptors (TLRs), Fc receptors (FcR), or nucleotide-binding oligomerization domain-like receptors (NLRPs), further activating microglia (181184)

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Primary Applications Reconstitution of lyophilized research compounds Laboratory dilution procedures Research reagent preparation Analytical and experimental applications Multi-use preserved aqueous diluent Product Information Sterile Water for Injection, USP Contains 0.9% benzyl alcohol as a preservative Multi-dose vial Manufactured by Hospira, a Pfizer company Intended for laboratory and research applications Research Use Only: This product is intended solely for laboratory research purposes

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