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In another study, the ability of RSV to inhibit RPE cell inflammation caused by hyperglycemia in vitro was evaluated and inhibition of VEGF, TGF1, COX2, IL6, and IL8 accumulations was observed in a dosedependent manner in the treated cells with RSV

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Specifically, apoA-I binds to ABCA1 and activates phosphatidylcholine lipases, which activate PKC leading to the movement of cellular cholesterol from intracellular stores to the plasma membrane for efflux, as well as PKC-mediated phosphorylation of ABCA1, which increases the transporters stability and efflux activity (782-784)

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In addition to being a raw material for biomass and an energy source, amino acids are also involved in key pathways in terms of cell growth, metabolism and immunity