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This anatomical configuration allows for efficient absorption of therapeutic agents, optimizing local drug concentration and maximizing therapeutic efficacy while minimizing systemic side effects

Chin J Clin Infect Dis

M., & Margolina, A

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Because all the fat that your body is breaking down whether its the belly flab you have been waiting to no longer hang over your jeans, or the fat on your thighs that make pulling up the pant legs from high school a non-possibility, has to go through the liver FIRST before then fully exiting your body in some way