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Detection of SOD enzyme activity The SOD-like activities of Mn 3 O 4 NPs, Mn@mHSA and Mn/TI@mHSA were assessed using the Superoxide Dismutase Assay Kit according to the manufacturers protocols

This suppression of CYP1A2 is relevant, as it metabolizes asthmatic and psychotic drugs, potentially increasing the risk of drug toxicity ( For instance, Mongolian gerbil studies have reported that quinestrol, an exogenous estrogen, modifies metabolizing enzymes

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At high concentrations, this interaction causes direct membrane destabilization, whereas lower concentrations promote endocytic entry (Steinstraesser et al., 2011

177 Similar results were reported for patients with and without Hunner lesions for whom multiple therapeutic hydrodistension with 100 cm H 2 O for 5 minutes, over several years, did not significantly change bladder capacity