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In the central nervous system, niacin is known as a key mediator of neuronal development and survival (37)

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AUC 0.893 without antihypertensive medications with the proven impact on the RAAS), as it was observed for ARR (AUC 0.765 with and AUC 0.845 without the interfering with RAAS antihypertensive drugs) (70)

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Finally, AuNPs could be used as X-ray contrast agent if their concentration in the brain is sufficiently high to allow for their detection, making them potential carriers for theranostic treatments [174]

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