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The loss of mitochondrial translation using 5 g/mL CAP, however, suppressed ACT-induced mistranslation and rescued mitoribosome decay, OPA1 processing and m to CAP levels (Figs

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One such example is the acrolein-induced activation of Nrf2 in vitro in endothelial cells leading to induction of heme-oxygenase-1, the enzyme that plays a major role in the cellular antioxidative response (Wu et al

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Abstract Inappropriate activation of c-mesenchymal-epithelial transition (MET), the receptor tyrosine kinase (RTK) for hepatocyte growth factor (HGF), has been implicated in tumorigenesis and represented a promising therapeutic target for developing anticancer agents

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