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The impact of microglial activation on bloodbrain barrier in brain diseases
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In addition to the recommendations already summarized by various lung associations, we would strongly recommend that consideration be given to include dietary interventions focused on increasing the fruit and vegetable intake as an important and immediately applicable approach to increasing antioxidants in individuals who have or are at risk of developing COPD
Abbreviations CCA: Cholangiocarcinoma SLC: Solute carrier FGFR: Fibroblast growth factor receptor IDH1: Isocitrate dehydrogenase 1 -KG: Alpha-ketoglutarate ROS: Reactive oxygen species ACSL4: Acyl-CoA synthetase long chain family member 4 LPCAT3: Lysophosphatidylcholine acyltransferase 3 GPX4: Glutathione hydroperoxidase 4 OGC: Oxoglutarate carrier PUFAs: Polyunsaturated fatty acids HR: Hazard ratio TCGA: The Cancer Genome Atlas GEO: Gene expression omnibus IHC: Immunohistochemistry m: Mitochondria membrane potential TMRE: Tetramethylrhodamine ethyl ester perchlorate ETC: Electron transport chain PEBP1: Phosphatidylethanolamine binding protein 1 Fer-1: Ferrostatin-1 IPA: Ingenuity pathway analysis NRF2: Nuclear factor erythroid 2-related factor 2 CUL3: Cullin3 CRLs: Cullin-RING E3 ligase complex HIF-1: Hypoxia inducible factor 1 subunit alpha GSH: Glutathione ALOX: Arachidonate lipoxygenase ICD: Immunogenic cell death DAMPs: Damage-associated molecular patterns HMGB1: High-mobility group box 1 ATP: Adenosine 5-triphosphate CRT: Calreticulin References Elvevi A, Laffusa A, Scaravaglio M, Rossi RE, Longarini R, Stagno AM, et al
Hashizume, R
