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We next investigated whether mitochondria are the source of ROS generation in RPE cells upon GSH depletion, we used MitoSOX Red to detect mitochondrial ROS (Fig

Chemotherapy & Radiation Support Traditional cancer treatments like radiation and chemotherapy contribute to oxidative stress and deplete Vitamin C causing additional cellular damage alongside their therapeutic effect

(PubMed) Smith AR, Shenvi SV, Widlansky M, Suh JH, Hagen TM

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67 HorvthE.BelaK.PapdiC.GallSzabadosL.TariI.et al (2015)

The levels of these peptides were upregulated in the epidermis, offering novel insights into the immunoregulatory mechanisms associated with skin aging (Cheung and Juan, 2017)