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It may have protective effects on the brain

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Tissue and free DNA-based epigenomics methods have been proposed for early detection, diagnosis, and treatment monitoring of various cancers, including colorectal cancer, lung cancer, breast cancer, bladder cancer, prostate cancer, and glioblastoma (Leal et al., 2020)

James PT, Rigby N, Leach R

IGF-1 signaling also plays a role in maintaining BBB integrity by promoting the expression of tight junction proteins and inhibiting the breakdown of the extracellular matrix (Freese et al., 2017)

One of them is based on the inhibition of endothelin 1 (ET-1), which, in addition to functioning as a mitogen, also has pro-angiogenic properties