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The search was conducted on July 8th, 2025, in all four databases

Fading is gradual and cumulative

10.1016/j.diff.2010.03.002 185 ZhaoG

Occludin has also been shown to be an important regulator of TJ assembly and functions (Van Itallie et al., 2010

Starting Concentration and Gradual Introduction Many dermatologists recommend starting with lower concentrations, under 0.5%, and gradually increasing to higher strengths as your skin acclimates