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TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL

Elderly patients may have normal B 12 levels with clinically significant B 12 deficiency

They overlap with depression, thyroid problems, sleep disorders, and vitamin D deficiency

When administered by IV, some research suggests it may improve mental clarity, memory, concentration and alertness

Blood samples taken at five and 13 years after the start of the study showed that average vitamin B12 levels were lower among participants on metformin at the five-year mark

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