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promote angiogenesis (the formation of new blood vessels)

The failing heartan engine out of fuel

In our study, rats acutely exposed to stress conditions present motor impairment, as evidenced by decreased crossing and rearing movements and rotarod activities

T.van der SchaftJ.van Os-MedendorpH.et al (2019)

10.1517/14728222.2016.1091882 11 BucanaC

Human monocyte-derived dendritic cells express TrkB, and BDNF modulates their maturation, implying that BDNF/TrkB can alter antigen-presenting cell function and subsequent T-cell priming ( Careful anatomical and temporal annotation of receptor signaling, together with explicit consideration of murinehuman differences in NGF/BDNF expression, Trk isoforms, ligand affinity and immune-cell repertoires, is required to relate cell-intrinsic effects to stromal and immune phenotypes and to gauge the translational limits of murine OS models