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The results show the role of cellcell interaction and intracellular NRF2-YAP signaling pathway in determining ferroptosis and show that malignant mutations in the NRF2-YAP signaling pathway can predict the response of cancer cells to future induction therapy for ferroptosis [72]

Wang D, Zheng J, Hu Q, Zhao C, Chen Q, Shi P, Chen Q, Zou Y, Zou D, Liu Q, Pei J, Wu X, Gao X, Ren J, Lin Z (2020) Magnesium protects against sepsis by blocking gasdermin D N-terminal-induced pyroptosis

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These findings highlight the potential of dual CYP17A1 and HDAC6 inhibition as a promising strategy to overcome resistance in GBM therapy, offering a new avenue for more effective treatments

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In the ATG5-ATG7-NCOA4 pathway, the process of ferritin-associated autophagy that is mediated by NCOA4 can increase the content of unstable iron in cells, thus promoting ferroptosis 33