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In whole-cell current clamp experiments, hyperpolarizing or depolarizing current pulses (500 ms, from 10 to 30 pA in 5-pA steps) were injected into neurons to determine input resistances or trigger action potentials

However, research in this area is still in its early stages, highlighting the need for further studies to determine the specific mechanisms, optimal dosages, and long-term safety of GPX4-targeted therapies

doi: 10.1016/j.neuron.2013.02.003 35

Die Lsung: Ein vollstndiger Kreislauf statt Einzelsubstanz Glutathion comp geht einen anderen Weg: Statt nur extern zugefhrtes Glutathion bereitzustellen, untersttzt es den gesamten Glutathion-Kreislauf

Q What interferes with the assay

Luminescent Rhenium(I) and iridium(III) polypyridine complexes as biological probes, imaging reagents, and photocytotoxic agents