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However, SMA-positive patients experienced reduced all-cause mortality compared to SMA-negative patients (median not reached vs 2.9 years, log-rank p=0.036

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There is moderate emperical support, as there are studies available on these KER's but there is a lack of information on dose-response relationships in this AOP

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This enzymatic complex has been implicated in many functions ranging from host defense to cellular signaling and the regulation of gene expression

doi: 10.3390/md17020130