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Furthermore, in models of Alzheimers disease (AD) and tauopathy, this intervention eliminates amyloid- and pathological tau, leading to improved memory performance

J.MorgensternR.2005Bioinformatic and enzymatic characterization of the MAPEG superfamily.2727(April 2005),16881703,0174-2464X 12

Core processes and disease relevance of autophagy with insights into transcriptional and epigenetic control Overview of cellular autophagy Autophagy is an evolutionarily conserved catabolic process by which cells degrade and recycle cytoplasmic components through lysosomal pathways

Several small molecules and protein-based compounds are under development to modulate GPX4 enzyme activity