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The predominantly hepatic metabolism of orforglipron does, however, raise the question of whether dose adjustment is needed in hepatic impairment, an issue that was addressed in dedicated hepatic impairment studies during the clinical development program

Determinants of treatment response in painful diabetic peripheral neuropathy: a combined deep sensory phenotyping and multimodal brain MRI study

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Polycythemia vera, a rare blood disorder, where careful medical oversight is appropriate

Analysis of lipolytic protein trafficking and interactions in adipocytes