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Front Pharmacol 8:18

Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging

Another region of equal scalp area affected by incipient alopecia in every subject was treated in the same way, using a lotion of equivalent composition but without the Oleuropein (active preparation 2): Ethanol 48.0% (v/v) Water 28.2% (v/v) Propanediol 20.0% (v/v) Ethoxy-glycol 1.5% (v/v) Sodium bicarbonate 0.5% (w/v) Glutathione / Vitamin F thioester 0.4% (w/v) Lactic acid 0.2% (w/v) Methyl nicotinate 0.05% (w/v) Another region of equal scalp area affected by incipient alopecia in every subject was treated in the same way, using a lotion of equivalent composition, but without the Glutathione /Vitamin F thioester (active compound 3): Ethanol 48.0% (v/v) Water 28.2% (v/v) Propanediol 20.0% (v/v) Ethoxy-glycol 1.5% (v/v) Oleuropein (from dry extract of olive leaf) 1.2% (w/v) Sodium bicarbonate 0.5% (w/v) Lactic acid 0.2% (w/v) Methyl nicotinate 0.05% (w/v) Another region of equal scalp area affected by incipient alopecia in every subject was treated in the same way, using a lotion of equivalent composition, but without the Glutathione/Vitamin F thioester (control preparation 1): Ethanol 49.0% (v/v) Water 28.2% (v/v) Propanediol 20.0% (v/v) Ethoxy-glycol 1.5% (v/v) Sodium bicarbonate 0.5% (w/v) Lactic acid 0.2% (w/v) Methyl nicotinate 0.05% (w/v) At the end of twenty-one days (Checkpoint 1) and forty -two days (Checkpoint 2) of treatment being performed, the trichological examination was performed using photo- tricogrammetry on 2 cm 2 randomly chosen treated areas and control areas each

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Curr Biol 15(2):154159 Verhoeven KJF, Jansen JJ, van Dijk PJ, Biere A (2010) Stress-induced DNA methylation changes and their heritability in asexual dandelions