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The encapsulation of dexamethasone in PLGA NPs allows for controlled release and targeted delivery, reducing systemic side effects and enhancing efficacy (169)

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The majority of research was determined to be at extreme risk of bias due to inadequate description of randomisation (25%, 3/12), allocation concealment (16.67%, 2/12), description of baseline characteristics (8.33%, 1/12), blinding of caregivers/researchers (8.33%, 1/12), selective reporting of results (8.33%, 1/12) and other sources (8.33%, 1/12)

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