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Description

Neutralizing antibodies against tirzepatide activity on the GIP or GLP-1 receptors and against native GIP or GLP-1 were detected in 2.8% and 2.7% and 0.8% and 0.1% respectively, of ZEPBOUND-treated patients in weight reduction clinical studies

Recent studies have highlighted the role of the TCA cycle and respiratory chain activity in coordinating amino acid metabolism and mitochondrial homeostasis