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These data and the proposed role for these residues indicate that SapM follows a serine-based alkaline-like mechanism of catalysis similar to that of Ec-AlkP and Ft-AcpA with S95 acting as the nucleophile

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The effect of smoking on clinical presentation and expression of TLR-2 and CD34 in Oral lichen Planus patients: clinical and immunohistochemical study

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Acknowledgements Figures 1, 2, 3 and 4 in this review were created using BioRender.com ( Funding This work was supported by the National Natural Science Foundation of China [grant numbers 81973498 and 81774283], National Science Foundation For Distinguished Young Scholars [grant numbers 82125037], the Joint Open Project of Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica and Yangtze River Pharmaceutical Group (No