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And chelates heavy metals like mercury and lead which can accumulate in and damage neurons

The maximum plasma concentrations (C(max)) of adducts for immediate release (IR) and extended release (ER) formulations were 0.108 (0.020) and 0.100 (0.028) nmol/mL serum, respectively, and were two orders of magnitude lower than the maximum APAP adduct levels previously reported in adults with acute liver failure secondary to APAP

doi: 10.1016/j.mehy.2010.08.036, 244

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The reason we advise 50 micrograms a day or 2,000 a week is because the less frequently you take vitamin B12, even at high doses, the percentage your body absorbs drops

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