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& Jerums, G

"A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family"

Oxidative stress was measured as a function of DCFDA fluorescence, a measure of general reactive oxygen species

Laboratory experiments have revealed that AS-IV reduces GSH levels, alters the size and structure of mitochondria in RPE cells, enhances cellular antioxidant capabilities to mitigate ferroptosis, and ultimately decreases high glucose-induced RPE cell death through the miR-138-5p/SIRT1/NFE2L2 pathway (Tang et al., 2022)

Mucosal Immunol 7(5):10791093

Activation of vascular endothelial growth factor receptor-3 in macrophages restrains TLR4-NF-B signaling and protects against endotoxin shock