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Description

attributed mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) to a defect in communication between nuclear and mitochondrial genomes

Intake recommendations vary according to the institution used as a reference

QL and ZN edited the manuscript

The prevalence among the general population is 1.17/1,000, with an incidence of 25/100,000 (2,3)

Kidney tissues were homogenized on ice with lysis buffer (0.1 g/mL) and centrifuged at 8000 rpm for 10 minutes at room temperature for the protein carbonyl immunoassay

The increasing complexity of neurological and neurodegenerative disorders, coupled with the paradigm shift toward precision medicine, has exposed the limitations of traditional clinical trial designs