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Biotin deficiency is rare but can occur in specific groups: High-Risk Groups: People with metabolic disorders or malnutrition Alcoholics and athletes Epilepsy patients , elderly , and those with gastrointestinal surgery Pregnant women (studies show 50% develop deficiency due to increased vitamin demand) Diabetes patients Dietary Causes: Long-term consumption of raw egg whites contains avidin , a protein that binds biotin and prevents absorption

Though it may sound disgusting, back then it was groundbreaking

Severe vitamin B12 deficiency in pregnancy mimicking HELLP syndrome. Case Reports in Obstetrics and Gynecology 2019 (2019)

Despite this, ongoing research continues to explore its therapeutic potential, including its effects on knee pain, liver tissue, and alternative therapies for various wounds and tissue injuries

The B12 when cold is thicker and can be more difficult to inject and ache after

The minimum evaluation period should be 2 to 3 weeks for most applications, with significant results typically emerging at the 4-week mark