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This loss of medium spiny neurons is due, in part, to altered BDNF transport that results in a reduction of BDNF release [17, 20]

Misfolded SOD1 associated with motor neuron mitochondria alters mitochondrial shape and distribution prior to clinical onset

Results: Among 188 adult LT recipients, 82% were male, median age at LT was 62 (interquartile range 57-66) years, and AFP at LT was 5.2 (3.1-11) ng/mL

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With 1 mM GABA, the mean POD activity decreased to 28.08 U/g FW, representing a percentage change of -33.17%