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burgdorferi species revealed that spirochaetes lack the classically defined virulence determinants common to a large number of microbial and, specifically, bacterial pathogens, such as lipopolysaccharides, specialized secretion systems, and toxins [Citation15,Citation16]

However, the extent to which such observations warrant the initiation of early intervention, as well as the efficacy of these interventions in altering the natural history of the disease, remains unsupported by prospective clinical evidence

Since NAC can protect cells from oxidative damage through direct (by reacting with oxidants) and indirect (by increasing GSH-Px) ways 16 , we proposed that NAC could attenuate the intestinal oxidative stress induced by -CG

However, recent results confirmed that glutamate, acetylcholine, serotonin, and GABA changes may also contribute to the pathology of the diseases

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