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Biol Trace Ele Res

Severe COVID-19: NLRP3 inflammasome dysregulated

In recent years, the relationship between high cholesterol levels and cancer development has been demonstrated [175] and also reconfirmed by the therapeutic potential of cholesterol-lowering drugs like statins in cancer patients [176]

This review dissects the core mechanistic pillars of this synergy such as insulin resistance, chronic low-grade inflammation, ectopic lipid deposition, and hormonal dysregulation

Researchers observed that treatment was associated with reduced p16-positive cell populations and changes in physical function parameters in aged animals [1]