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Dihexa was developed as a structurally modified analogue of angiotensin IV and retains key features of the parent scaffold while incorporating modifications designed to alter physicochemical and pharmacological properties

10.1016/j.bbr.2020.112919 Summary Keywords retina, ischemia, BPC 157, L-NAME, rats Citation Zlatar M, Kokot A, Vuletic LB, Masnec S, Kralj T, Perisa MM, Barisic I, Radic B, Milanovic K, Drmic D, Seiwerth S and Sikiric P (2021) BPC 157 as a Therapy for Retinal Ischemia Induced by Retrobulbar Application of L-NAME in Rats

For OPERA (release v2.0), the pKa model currently available on the Github repository is available as both a command line module and in the form of a user-friendly graphical interface [45]

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In animal studies, BPC-157 accelerates tendon to bone healing and antagonizes the tissue damage induced by corticosteroids, indicating it could help restore local tissue integrity that is important for embryo implantation and uterine function

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