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[DOI] [PMC free article] [PubMed] [Google Scholar] 76.Zimmermann P., Curtis N

Tools such as QIIME2, MetaPhlAn, and HUMAnN [125] (Tables 1 and 2) enable reproducible and high-resolution functional profiling of microbial communities, while multivariate integration platforms like MixOmics [126] (Table2) and MTD (Meta-Transcriptome Detector) [127] (Table 2) or matrix factorization approaches such as PLIER [128] (Table 2) and HONMF [129] (Table 2) have been developed to integrate heterogeneous omics data and uncover cross-kingdom associations

Once B12 levels are stabilised, the frequency typically reduces to every 2-3 months, although the exact frequency should be prescribed by a healthcare provider

This change may be associated with the depletion of carbohydrate reserves that occur during fasting 62

The retrieval of tissue and clinical data was approved by the Institutional Review Board of Ethics of Ningbo University (NBU-2022-123)

Vilar Gomez E, Sanchez Rodriguez Y, Torres Gonzalez A, et al