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Potential applications of antioxidants a review

for example, valproic acid raises ammonia levels, and added glycine could theoretically exacerbate hyperammonemia

313,317 Moreover, MCP-1, a key chemokine in central nervous system inflammation, can disrupt bloodbrain barrier integrity by targeting tight junctions

For a broader explanation of ATP production, the electron transport chain, SOD enzymes and oxidative damage, review What Are Mitochondria

Extensive research indicates that NRF2 plays a pivotal role in regulating ferroptosis due to its diverse functions in iron, lipid, and amino acid metabolism (Shakya et al., 2023