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doi: 10.1016/j.chembiol.2020.10.010

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To reflect the metabolite (CARs) content at different concentrations of PHB intoxication and observe metabolite clustering, in this work a hierarchical clustering analysis was performed based on the metabolite content and the results were represented as a heat map (Figure 2

DC661 produced a significant increase in LDH release, and this could not be reversed by apoptosis, necroptosis, or ferroptosis inhibition (Supplemental Figure 5C)