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To identify the mechanisms underlying the cytotoxic effects of the NUPR1 inhibition in phBECs, we performed gene expression analysis of ferroptosis-related genes, lipid peroxidation assays, Annexin V/PI apoptosis/necrosis analysis and western blot analysis of ferroptosis and apoptosis-related genes

Plasma alpha-synuclein levels are increased in patients with obstructive sleep apnea syndrome

These findings are encouraging, though more large-scale trials are needed

Unreconstituted lyophilized powder can be stored at room temperature short-term but remains most stable under refrigeration

Effects vary depending on the type and severity of injury

Thony B, Blau N