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Keywords: Ethanol-toacetaldehyde metabolism, alcohol dehydrogenase (ADH), aldehyde dehydrogenase (ALDH), acetaldehyde, acetate, cytochrome P450 2E1 (CYP2E1), catalase, reactive oxygen species (ROS), blood alcohol concentration (BAC), liver, stomach, brain, fetal alcohol effects, genetics and heredity, ethnic group, hypoxia The effects of alcohol (i.e., ethanol) on various tissues depend on its concentration in the blood (blood alcohol concentration [BAC]) over time