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Interim analysis of the EAGLE trial: an open-label study to assess the long-term safety and tolerability of bardoxolone methyl in patients with alport syndrome: PO1300

10.1016/j.redox.2020.101509 13 BuenoM.LaiY

Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions

Among over 20 distinct RCD modalities reported, ferroptosis, described as a ROS-dependent non-apoptotic iron-driven cell death [496], has attracted considerable attention as a potential therapeutic target in cancer [497]

Patients were randomized to receive one of the following: Treatment continued in both arms until disease progression or unacceptable toxicity