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41589_2021_915_MOESM10_ESM.mpeg Supplementary Video 8 Representative movie for 100 ns MD simulation of GPX4 U46C-K48A with the camera zoomed in for a close-up of the active site

10.1002/jcp.22218 Mavalli MD, DiGirolamo DJ, Fan Y, Riddle RC, Campbell KS, van Groen T, Frank SJ, Sperling MA, Esser KA, Bamman MM, Clemens TL: Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice

FIGURE 2 3.1 Etiology correlation In terms of etiology, risk factors for VICD such as hyperlipidemia (Jia et al., 2020), diabetes (Prajjwal et al., 2023), atherosclerosis (Huang et al., 2021), and other diseases are characterized by intracellular metabolic pathways disorders and increased oxidative damage, which are associated with ferroptosis (Figure 2)

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Scavenger receptor class B type I-mediated reverse cholesterol transport is inhibited by advanced glycation end products