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they can be dramatic

Disruption of the balance leads to the autoantibody formation

An earlier 12-week Phase 2b trial with 300 obese patients produced more encouraging numbers: the 1 mg dose group lost an average of 2.8 kg compared to 0.8 kg for placebo, with small but consistent improvements in cholesterol profiles and a reduction in patients with impaired glucose tolerance

Future work will therefore examine these outstanding issues

Possible mechanisms of homocysteine toxicity